Multiplex Transcription Factor Assays, Transcription Factor, Multiplex Assays

Marligen’s Multiplex Transcription Factor Assays employ a powerful multiplexing approach for simultaneously measuring the binding of many different transcription factors to their

Multiplex Transcription Factor Profiling Kit

unique regulatory DNA elements. The technology dramatically accelerates studies ranging from basic research in signal transduction and proteomics to target validation, compound screening, toxicity testing and disease characterization.
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Advantages:

Speed, ease of use and quantitation vastly outperform EMSAs
Excellent sensitivity, specificity, reproducibility and dynamic range versus ELISAs
Unparalled speed of data acquisition - ~2,000 results in 3 hours
Small sample requirement saves time and money
Assays validated in many cells lines, primary cells and tissues from humans, monkeys and rodents
Multiple binding sites in assay mimics in vivo binding conditions

Marligen offers 20 different assays that are available in a pre-mixed 20-plex or as single-plexes that can be combined to make your own custom panel. These assays include AP-1, AP2, AR, CRE-ATF, CREB, E2F1-5, E2F6, EGR, GATA, HNF1, HNF4, ISRE, Myc-Max, NF-1, NFkB, p53, PPAR, SMAD2/3, SP1, and YY1. A Multiplex Transcription Factor Profiling Kit (Cat. No. 11955-096) contains all of the common assay reagents and is required to run a custom multiplex panel. All of these multiplex assays are formatted to be read on the Luminex Reader. Find out more details about the Luminex xMAP® technology and instrumentation.

For researchers interested in trying out our assays but do not have access to the Luminex instrumentation or who would prefer to outsource the work, our experienced technical staff also performs Testing Services.

Order Multiplex Transcription Factor Assays

Catalog No.

Item Name

Transcription Factor Binding Site (s)

Size

U.S. List Price (US$)

AM100053 Pkg Insert	Multiplex Transcription Factor Profiling Kit (20-plex) (11954-096)	AP-1, AP2, AR, CRE-ATF, CREB, E2F1-5, E2F6, EGR, GATA, HNF1, HNF4, ISRE, Myc-Max, NF-1, NF?B, p53, PPAR, SMAD2/3, SP1, YY1	96 rxns	$2986
PM100001 Pkg Insert	Nuclear Extraction Kit (11906-100)	NA	100 rxns	$139
PM100003 Pkg Insert	Protein Control (NF-1/NFkB) (11934-001)	NA	20μL	$85
AM100086	Multiplex Transcription Factor Testing Service (50-plex) (11907-001)	AP-1, AP2, AML-1, AP4, AR, CRE-ATF, C/EBP?, C/EBP?, C/EBP?, CREB, E2F1-5, E2F6, EGR, ER, ETS, GATA, HFH2/3, HIC-1, HIF, HNF-1, HNF-3, HNF-4, HSF-1, ISRE, MEF-2, MTF1, c-Myb, Myc-Max, NFAT, NF-1, NF?B, NFY1, Octamer, p53, PAX6, PBX, PLZF, PPAR, SAF-1, SOX9, STAT, SREBP, SMAD1/5, SMAD 2/3, SP1, SRE, TGIF, TAL1, TCF/LEF and YY1	96 rxns	$5750

To order these products, or contact technical services, please visit www.origene.com/about/contact_us/
For international pricing and orders please contact one of our international distributors.

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