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SH2 Domains

technical notes faqs
 
Marligen offers phosphoprofiling tools that exploit Src homology 2 (SH2) domains for profiling the tyrosine phosphoproteome that are ideal for generating a “snap-shot” of the phosphorylation status of the cellular environment. The SH2 Domain probes are recombinant GST fusion proteins containing specific SH2 domains for the detection of phosphotyrosine profiles by far-Western blotting, ELISAs and immunochemistry.
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Advantages:

  • Yields biologically relevant “snap-shot” of cellular phosphotyrosine profiles
  • Easily identify differences in signaling between normal and diseased or treated samples
  • More sensitive and specific than anti-phosphotyrosine immunoblotting
  • Results that are easy to interpret and allows specific pathway analysis
  • Ideal for ELISA and immunohistochemistry applications as well as far-Western blotting

Order SH2 Domains

  Catalog No. Item Name Size U.S. List Price (US$)
PM100005
Pkg Insert
Whole Cell Extraction Reagent (11941-100) 100 rxns $139
PP100001
Pkg Insert
Abl SH2 Domain Probe (11908-050) 50 μg $273
PP100002
Pkg Insert
PLC gamma SH2 Domain Probe (11909-050) 50 μg $273
PP100003
Pkg Insert
Lck SH2 Domain Probe (11910-050) 50 μg $273
PP100004
Pkg Insert
Nck SH2 Domain Probe (11911-050) 50 μg $273
PP100005
Pkg Insert
Ras-GAP SH2 Domain Probe (11912-050) 50 μg $273
PP100006
Pkg Insert
PI3Kinase SH2 Domain Probe (11913-050) 50 μg $273
PP100007
Pkg Insert
SHP-2 SH2 Domain Probe (11914-050) 50 μg $273
PP100008
Pkg Insert
Grb-2 SH2 Domain Probe (11915-050) 50 μg $273
PP100009
Pkg Insert
Src SH2 Domain Probe (11916-050) 50 μg $273
PP100010
Pkg Insert
Crk SH2 Domain Probe (11917-050) 50 μg $273

For international pricing and orders please contact one of our international distributors.

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